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Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice

Cachexia is a systemic wasting syndrome that increases cancer-associated mortality. How cachexia progressively and differentially impacts distinct tissues is largely unknown. Here, we find that the heart and skeletal muscle undergo wasting at early stages and are the tissues transcriptionally most i...

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Detalles Bibliográficos
Autores principales: Graca, Flavia A., Stephan, Anna, Wang, Yong-Dong, Shirinifard, Abbas, Jiao, Jianqin, Vogel, Peter, Labelle, Myriam, Demontis, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983329/
https://www.ncbi.nlm.nih.gov/pubmed/36640353
http://dx.doi.org/10.1016/j.celrep.2022.111934