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Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice
Cachexia is a systemic wasting syndrome that increases cancer-associated mortality. How cachexia progressively and differentially impacts distinct tissues is largely unknown. Here, we find that the heart and skeletal muscle undergo wasting at early stages and are the tissues transcriptionally most i...
Autores principales: | Graca, Flavia A., Stephan, Anna, Wang, Yong-Dong, Shirinifard, Abbas, Jiao, Jianqin, Vogel, Peter, Labelle, Myriam, Demontis, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983329/ https://www.ncbi.nlm.nih.gov/pubmed/36640353 http://dx.doi.org/10.1016/j.celrep.2022.111934 |
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