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Neutrophil Extracellular Traps Induce Alveolar Macrophage Pyroptosis by Regulating NLRP3 Deubiquitination, Aggravating the Development of Septic Lung Injury

BACKGROUND: Uncontrolled inflammation is a typical feature of sepsis-related lung injury. The key event in the progression of lung injury is Caspase-1-dependent alveolar macrophage (AM) pyroptosis. Similarly, neutrophils are stimulated to release neutrophil extracellular traps (NETs) to participate...

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Detalles Bibliográficos
Autores principales: Cui, Yamei, Yang, Ying, Tao, Wenqiang, Peng, Wei, Luo, Deqiang, Zhao, Ning, Li, Shuangyan, Qian, Kejian, Liu, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983334/
https://www.ncbi.nlm.nih.gov/pubmed/36876152
http://dx.doi.org/10.2147/JIR.S366436