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Mechanistic Study of Schisandra chinensis Fruit Mixture Based on Network Pharmacology, Molecular Docking and Experimental Validation to Improve the Inflammatory Response of DKD Through AGEs/RAGE Signaling Pathway

BACKGROUND: Diabetic kidney disease (DKD) is a major cause of end-stage renal disease (ESRD), and inflammation is the main causative mechanism. Schisandra chinensis fruit Mixture (SM) is an herbal formulation that has been used for a long time to treat DKD. However, its pharmacological and molecular...

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Detalles Bibliográficos
Autores principales: Li, Hongdian, Dong, Ao, Li, Na, Ma, Yu, Zhang, Sai, Deng, Yuanyuan, Chen, Shu, Zhang, Mianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983444/
https://www.ncbi.nlm.nih.gov/pubmed/36875720
http://dx.doi.org/10.2147/DDDT.S395512