Integrative genetic and single cell RNA sequencing analysis provides new clues to the amyotrophic lateral sclerosis neurodegeneration

INTRODUCTION: The gradual loss of motor neurons (MNs) in the brain and spinal cord is a hallmark of amyotrophic lateral sclerosis (ALS), but the mechanisms underlying neurodegeneration in ALS are still not fully understood. METHODS: Based on 75 ALS-pathogenicity/susceptibility genes and large-scale...

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Detalles Bibliográficos
Autores principales: Liu, Hankui, Guan, Liping, Deng, Min, Bolund, Lars, Kristiansen, Karsten, Zhang, Jianguo, Luo, Yonglun, Zhang, Zhanchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983639/
https://www.ncbi.nlm.nih.gov/pubmed/36875658
http://dx.doi.org/10.3389/fnins.2023.1116087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983639/
https://www.ncbi.nlm.nih.gov/pubmed/36875658
http://dx.doi.org/10.3389/fnins.2023.1116087

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