Genomic Patterns of Malignant Peripheral Nerve Sheath Tumor (MPNST) Evolution Correlate with Clinical Outcome and Are Detectable in Cell-Free DNA

Malignant peripheral nerve sheath tumor (MPNST), an aggressive soft-tissue sarcoma, occurs in people with neurofibromatosis type 1 (NF1) and sporadically. Whole-genome and multiregional exome sequencing, transcriptomic, and methylation profiling of 95 tumor samples revealed the order of genomic even...

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Detalles Bibliográficos
Autores principales: Cortes-Ciriano, Isidro, Steele, Christopher D., Piculell, Katherine, Al-Ibraheemi, Alyaa, Eulo, Vanessa, Bui, Marilyn M., Chatzipli, Aikaterini, Dickson, Brendan C., Borcherding, Dana C., Feber, Andrew, Galor, Alon, Hart, Jesse, Jones, Kevin B., Jordan, Justin T., Kim, Raymond H., Lindsay, Daniel, Miller, Colin, Nishida, Yoshihiro, Proszek, Paula Z., Serrano, Jonathan, Sundby, R. Taylor, Szymanski, Jeffrey J., Ullrich, Nicole J., Viskochil, David, Wang, Xia, Snuderl, Matija, Park, Peter J., Flanagan, Adrienne M., Hirbe, Angela C., Pillay, Nischalan, Miller, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983734/
https://www.ncbi.nlm.nih.gov/pubmed/36598417
http://dx.doi.org/10.1158/2159-8290.CD-22-0786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983734/
https://www.ncbi.nlm.nih.gov/pubmed/36598417
http://dx.doi.org/10.1158/2159-8290.CD-22-0786

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