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Activation of an actin signaling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformation
Alterations in the expression or function of cell adhesion molecules have been implicated in all steps of tumor progression. Among those, P-cadherin is highly enriched in basal-like breast carcinomas, playing a central role in cancer cell self-renewal, collective cell migration and invasion. To esta...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983776/ https://www.ncbi.nlm.nih.gov/pubmed/36808468 http://dx.doi.org/10.1242/dmm.049652 |