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The identification of mediating effects using genome-based restricted maximum likelihood estimation
Mediation analysis is commonly used to identify mechanisms and intermediate factors between causes and outcomes. Studies drawing on polygenic scores (PGSs) can readily employ traditional regression-based procedures to assess whether trait M mediates the relationship between the genetic component of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983879/ https://www.ncbi.nlm.nih.gov/pubmed/36809357 http://dx.doi.org/10.1371/journal.pgen.1010638 |