Knockdown of deleterious miRNA in progenitor cell–derived small extracellular vesicles enhances tissue repair in myocardial infarction

Small extracellular vesicles (sEVs) play a critical role in cardiac cell therapy by delivering molecular cargo and mediating cellular signaling. Among sEV cargo molecule types, microRNA (miRNA) is particularly potent and highly heterogeneous. However, not all miRNAs in sEV are beneficial. Two previo...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Hyun-Ji, Hoffman, Jessica R., Brown, Milton E., Bheri, Sruti, Brazhkina, Olga, Son, Young Hoon, Davis, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984177/
https://www.ncbi.nlm.nih.gov/pubmed/36867699
http://dx.doi.org/10.1126/sciadv.abo4616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984177/
https://www.ncbi.nlm.nih.gov/pubmed/36867699
http://dx.doi.org/10.1126/sciadv.abo4616

Ejemplares similares