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Knockdown of deleterious miRNA in progenitor cell–derived small extracellular vesicles enhances tissue repair in myocardial infarction
Small extracellular vesicles (sEVs) play a critical role in cardiac cell therapy by delivering molecular cargo and mediating cellular signaling. Among sEV cargo molecule types, microRNA (miRNA) is particularly potent and highly heterogeneous. However, not all miRNAs in sEV are beneficial. Two previo...
Autores principales: | Park, Hyun-Ji, Hoffman, Jessica R., Brown, Milton E., Bheri, Sruti, Brazhkina, Olga, Son, Young Hoon, Davis, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984177/ https://www.ncbi.nlm.nih.gov/pubmed/36867699 http://dx.doi.org/10.1126/sciadv.abo4616 |
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