Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins

Alternative precursor messenger RNA splicing is instrumental in expanding the proteome of higher eukaryotes, and changes in 3′ splice site (3'ss) usage contribute to human disease. We demonstrate by small interfering RNA–mediated knockdowns, followed by RNA sequencing, that many proteins first...

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Detalles Bibliográficos
Autores principales: Dybkov, Olexandr, Preußner, Marco, El Ayoubi, Leyla, Feng, Vivi-Yun, Harnisch, Caroline, Merz, Kilian, Leupold, Paula, Yudichev, Peter, Agafonov, Dmitry E., Will, Cindy L., Girard, Cyrille, Dienemann, Christian, Urlaub, Henning, Kastner, Berthold, Heyd, Florian, Lührmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984181/
https://www.ncbi.nlm.nih.gov/pubmed/36867703
http://dx.doi.org/10.1126/sciadv.adf1785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984181/
https://www.ncbi.nlm.nih.gov/pubmed/36867703
http://dx.doi.org/10.1126/sciadv.adf1785

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