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The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities

Alteration of neuronal protein processing is often associated with neurological disorders and is highly dependent on cellular protein trafficking. A prime example is the amyloidogenic processing of amyloid precursor protein (APP) in intracellular vesicles, which plays a key role in age-related cogni...

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Detalles Bibliográficos
Autores principales: Brandimarti, Renato, Irollo, Elena, Meucci, Olimpia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984340/
https://www.ncbi.nlm.nih.gov/pubmed/36576708
http://dx.doi.org/10.1007/s12035-022-03153-2