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The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
Alteration of neuronal protein processing is often associated with neurological disorders and is highly dependent on cellular protein trafficking. A prime example is the amyloidogenic processing of amyloid precursor protein (APP) in intracellular vesicles, which plays a key role in age-related cogni...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984340/ https://www.ncbi.nlm.nih.gov/pubmed/36576708 http://dx.doi.org/10.1007/s12035-022-03153-2 |