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Expression of DNA mismatch repair proteins in melanoma patients treated with immune checkpoint inhibitors

PURPOSE: To investigate the protein expression of DNA mismatch repair (MMR) proteins in patients with cutaneous melanoma (CM) under immune checkpoint inhibitor (ICI) therapy. METHODS: Immunohistochemistry was performed on tumor tissue for MMR proteins MLH1, MSH2, MSH6, and PMS2 in 50 metastatic CM p...

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Detalles Bibliográficos
Autores principales: Gambichler, T., Finis, C., Abu Rached, N., Scheel, C. H., Becker, J. C., Lang, K., Käfferlein, H. U., Brüning, T., Abolmaali, N., Susok, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984342/
https://www.ncbi.nlm.nih.gov/pubmed/35419731
http://dx.doi.org/10.1007/s00432-022-04002-4