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Celsr2 Knockout Alleviates Inhibitory Synaptic Stripping and Benefits Motoneuron Survival and Axon Regeneration After Branchial Plexus Avulsion

Axotomy-induced synaptic stripping modulates survival and axon regeneration of injured motoneurons. Celsr2 is supposed to mediate homophilic interactions of neighboring cells during development, and its role in synaptic stripping remains unknow. In a model of brachial plexus avulsion, Celsr2 knockou...

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Detalles Bibliográficos
Autores principales: Yu, Lingtai, Liu, Mengfan, Li, Fuxiang, Wang, Qianghua, Wang, Meizhi, So, Kwok-Fai, Qu, Yibo, Zhou, Libing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984348/
https://www.ncbi.nlm.nih.gov/pubmed/36593433
http://dx.doi.org/10.1007/s12035-022-03198-3