Cargando…

Celsr2 Knockout Alleviates Inhibitory Synaptic Stripping and Benefits Motoneuron Survival and Axon Regeneration After Branchial Plexus Avulsion

Axotomy-induced synaptic stripping modulates survival and axon regeneration of injured motoneurons. Celsr2 is supposed to mediate homophilic interactions of neighboring cells during development, and its role in synaptic stripping remains unknow. In a model of brachial plexus avulsion, Celsr2 knockou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Lingtai, Liu, Mengfan, Li, Fuxiang, Wang, Qianghua, Wang, Meizhi, So, Kwok-Fai, Qu, Yibo, Zhou, Libing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984348/ https://www.ncbi.nlm.nih.gov/pubmed/36593433 http://dx.doi.org/10.1007/s12035-022-03198-3

Ejemplares similares

Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human
por: Wen, Quan, et al.
Publicado: (2022)

Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons
por: Feng, Jia, et al.
Publicado: (2016)

Celsr3 Inactivation in the Brainstem Impairs Rubrospinal Tract Development and Mouse Behaviors in Motor Coordination and Mechanic-Induced Response
por: Chen, Boli, et al.
Publicado: (2022)

Functional Motor Recovery from Motoneuron Axotomy Is Compromised in Mice with Defective Corticospinal Projections
por: Ding, Yuetong, et al.
Publicado: (2014)

Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion
por: Huang, Yanfeng, et al.
Publicado: (2022)

GAP-43 expression correlates with spinal motoneuron regeneration following root avulsion
por: Yuan, Qiuju, et al.
Publicado: (2009)

Identification of the Avulsion-Injured Spinal Motoneurons
por: Tan, Min, et al.
Publicado: (2015)

Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity
por: Zhou, Qinji, et al.
Publicado: (2021)

Spinal root avulsion: an excellent model for studying motoneuron degeneration and regeneration after severe axonal injury
por: Ruven, Carolin, et al.
Publicado: (2014)

Erratum to: Identification of the Avulsion-Injured Spinal Motoneurons
por: Tan, Min, et al.
Publicado: (2015)

Ventral root re-implantation is better than peripheral nerve transplantation for motoneuron survival and regeneration after spinal root avulsion injury
por: Su, Huanxing, et al.
Publicado: (2013)

Systematic expression analysis of the CELSR family reveals the importance of CELSR3 in human lung adenocarcinoma
por: Li, Yishuai, et al.
Publicado: (2021)

Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity
por: Basta, Lena P., et al.
Publicado: (2023)

Berberine enhances L1 expression and axonal remyelination in rats after brachial plexus root avulsion
por: Chen, Shuangxi, et al.
Publicado: (2020)

EGb761 protects motoneurons against avulsion-induced oxidative stress in rats
por: Cheng, Xiao, et al.
Publicado: (2010)

Lithium enhances survival and regrowth of spinal motoneurons after ventral root avulsion
por: Fu, Rao, et al.
Publicado: (2014)

The Demography of Traumatic Brachial Plexus Avulsion Injuries
por: Viswamadesh, Ramachandran, et al.
Publicado: (2022)

Time-specific microRNA changes during spinal motoneuron degeneration in adult rats following unilateral brachial plexus root avulsion: ipsilateral vs. contralateral changes
por: Tang, Ying, et al.
Publicado: (2014)

The Role of inab in Axon Morphology of an Identified Zebrafish Motoneuron
por: Van Ryswyk, Liesl, et al.
Publicado: (2014)

Axon initial segment geometry in relation to motoneuron excitability
por: Rotterman, Travis M., et al.
Publicado: (2021)

Impact of acute inflammation on spinal motoneuron synaptic plasticity following ventral root avulsion
por: Barbizan, Roberta, et al.
Publicado: (2010)

Branchial Cysts
Publicado: (1929)

Long-Term Outcome of Brachial Plexus Reimplantation After Complete Brachial Plexus Avulsion Injury
por: Kachramanoglou, Carolina, et al.
Publicado: (2017)

Identification of Novel CELSR1 Mutations in Spina Bifida
por: Lei, Yunping, et al.
Publicado: (2014)

Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease
por: Selvaraj, Bhuvaneish Thangaraj, et al.
Publicado: (2012)

Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr
por: Salehi, Saeede, et al.
Publicado: (2023)

Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones
por: Irvine, Sian F., et al.
Publicado: (2018)

Embryonic motor activity and implications for regulating motoneuron axonal pathfinding in zebrafish
por: Menelaou, Evdokia, et al.
Publicado: (2008)

ccdc80-l1 Is Involved in Axon Pathfinding of Zebrafish Motoneurons
por: Brusegan, Chiara, et al.
Publicado: (2012)

Axon-somatic back-propagation in detailed models of spinal alpha motoneurons
por: Balbi, Pietro, et al.
Publicado: (2015)

A novel mutation in CELSR1 is associated with hereditary lymphedema
por: Gonzalez-Garay, M. L., et al.
Publicado: (2016)

CELSR2 is a candidate susceptibility gene in idiopathic scoliosis
por: Einarsdottir, Elisabet, et al.
Publicado: (2017)

Elevated CELSR3 expression is associated with hepatocarcinogenesis and poor prognosis
por: Ouyang, Xiwu, et al.
Publicado: (2020)

Nociceptive Afferents to the Premotor Neurons That Send Axons Simultaneously to the Facial and Hypoglossal Motoneurons by Means of Axon Collaterals
por: Dong, Yulin, et al.
Publicado: (2011)

Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function
por: Briese, Michael, et al.
Publicado: (2020)

Branchial Cleft Cyst
por: Nahata, Vaishali
Publicado: (2016)

Neuropathic pain after brachial plexus avulsion - central and peripheral mechanisms
por: Teixeira, Manoel Jacobsen, et al.
Publicado: (2015)

Neuronal BDNF Signaling Is Necessary for the Effects of Treadmill Exercise on Synaptic Stripping of Axotomized Motoneurons
por: Krakowiak, Joey, et al.
Publicado: (2015)

Changes in the amounts of cytoskeletal proteins within the perikarya and axons of regenerating frog motoneurons
Publicado: (1983)

Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish
por: Spiró, Zoltán, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cru04p4l8ti9atihsba5agvmhk