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Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies

OBJECTIVES: Perioperative chemo-(radio-) therapy is the accepted standard in European patients with locally advanced adenocarcinoma of the esophagogastric junction or stomach (AEG/AS). However, 30–85% of patients do not respond to this treatment. The aim of our study was the identification of predic...

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Detalles Bibliográficos
Autores principales: Kleo, Karsten, Jovanovic, Vladimir M., Arndold, Alexander, Lehmann, Annika, Lammert, Hedwig, Berg, Erika, Harloff, Hannah, Treese, Christoph, Hummel, Michael, Daum, Severin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984352/
https://www.ncbi.nlm.nih.gov/pubmed/35246724
http://dx.doi.org/10.1007/s00432-022-03944-z