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The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation

Netrin-1 is a bifunctional chemotropic guidance cue that plays key roles in diverse cellular processes including axon pathfinding, cell migration, adhesion, differentiation, and survival. Here, we present a molecular understanding of netrin-1 mediated interactions with glycosaminoglycan chains of di...

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Detalles Bibliográficos
Autores principales: Meier, Markus, Gupta, Monika, Akgül, Serife, McDougall, Matthew, Imhof, Thomas, Nikodemus, Denise, Reuten, Raphael, Moya-Torres, Aniel, To, Vu, Ferens, Fraser, Heide, Fabian, Padilla-Meier, Gay Pauline, Kukura, Philipp, Huang, Wenming, Gerisch, Birgit, Mörgelin, Matthias, Poole, Kate, Antebi, Adam, Koch, Manuel, Stetefeld, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984387/
https://www.ncbi.nlm.nih.gov/pubmed/36869049
http://dx.doi.org/10.1038/s41467-023-36692-w