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Application of a genetic signature of late GU toxicity in SCIMITAR, a Post-op SBRT trial

Predictors of genitourinary toxicity after post-prostatectomy radiotherapy remain elusive. A previously defined germline DNA signature (PROSTOX) has shown predictive ability for late grade ≥ 2 GU toxicity after intact prostate stereotactic body radiotherapy. We explore whether PROSTOX would predict...

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Detalles Bibliográficos
Autores principales: Kishan, Amar U., Marco, Nicholas, Ma, Ting Martin, Steinberg, Michael L., Sachdeva, Ankush, Cao, Minsong, Ballas, Leslie K., Rietdorf, Emily, Telesca, Donatello, Weidhaas, Joanne B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984404/
https://www.ncbi.nlm.nih.gov/pubmed/36880064
http://dx.doi.org/10.1016/j.ctro.2023.100594