Improving adenine and dual base editors through introduction of TadA-8e and Rad51DBD

Base editors, including dual base editors, are innovative techniques for efficient base conversions in genomic DNA. However, the low efficiency of A-to-G base conversion at positions proximal to the protospacer adjacent motif (PAM) and the A/C simultaneous conversion of the dual base editor hinder t...

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Detalles Bibliográficos
Autores principales: Xue, Niannian, Liu, Xu, Zhang, Dan, Wu, Youming, Zhong, Yi, Wang, Jinxin, Fan, Wenjing, Jiang, Haixia, Zhu, Biyun, Ge, Xiyu, Gonzalez, Rachel V. L., Chen, Liang, Zhang, Shun, She, Peilu, Zhong, Zhilin, Sun, Jianjian, Chen, Xi, Wang, Liren, Gu, Zhimin, Zhu, Ping, Liu, Mingyao, Li, Dali, Zhong, Tao P., Zhang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984408/
https://www.ncbi.nlm.nih.gov/pubmed/36869044
http://dx.doi.org/10.1038/s41467-023-36887-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984408/
https://www.ncbi.nlm.nih.gov/pubmed/36869044
http://dx.doi.org/10.1038/s41467-023-36887-1

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