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Opsin 3 mediates UVA-induced keratinocyte supranuclear melanin cap formation

Solar ultraviolet (UV) radiation-induced DNA damage is a major risk factor for skin cancer development. UV-induced redistribution of melanin near keratinocyte nuclei leads to the formation of a supranuclear cap, which acts as a natural sunscreen and protects DNA by absorbing and scattering UV radiat...

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Detalles Bibliográficos
Autores principales: Lan, Yinghua, Zeng, Wen, Wang, Yu, Dong, Xian, Shen, Xiaoping, Gu, Yangguang, Zhang, Wei, Lu, Hongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984416/
https://www.ncbi.nlm.nih.gov/pubmed/36869204
http://dx.doi.org/10.1038/s42003-023-04621-8