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Blockage of PPARγ T166 phosphorylation enhances the inducibility of beige adipocytes and improves metabolic dysfunctions

Beige adipocytes in mammalian white adipose tissue (WAT) can reinforce fat catabolism and energy expenditure. Promoting beige adipocyte biogenesis is a tantalizing tactic for combating obesity and its associated metabolic disorders. Here, we report that a previously unidentified phosphorylation patt...

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Detalles Bibliográficos
Autores principales: Yang, Nanfei, Wang, Yuxin, Tian, Qiang, Wang, Qiuping, Lu, Yan, Sun, Luchen, Wang, Sijie, Bei, Yuncheng, Ji, Jianguo, Zhou, Hu, Yang, Wei, Yao, Pengju, Zhu, Wenyuan, Sun, Lingyun, Huang, Zhifeng, Li, Xiaokun, Shen, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984430/
https://www.ncbi.nlm.nih.gov/pubmed/36329235
http://dx.doi.org/10.1038/s41418-022-01077-x