Brexanolone therapeutics in post-partum depression involves inhibition of systemic inflammatory pathways

BACKGROUND: Brexanolone has rapid, long-lasting, and remarkable efficacy in the treatment of post-partum depression (PPD). We test the hypothesis that brexanolone inhibits proinflammatory modulators and macrophage activation in PPD patients, which may promote clinical recovery. METHODS: PPD patients...

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Detalles Bibliográficos
Autores principales: Balan, Irina, Patterson, Riah, Boero, Giorgia, Krohn, Holly, O'Buckley, Todd K., Meltzer-Brody, Samantha, Morrow, A. Leslie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984433/
https://www.ncbi.nlm.nih.gov/pubmed/36801618
http://dx.doi.org/10.1016/j.ebiom.2023.104473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984433/
https://www.ncbi.nlm.nih.gov/pubmed/36801618
http://dx.doi.org/10.1016/j.ebiom.2023.104473

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