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Brexanolone therapeutics in post-partum depression involves inhibition of systemic inflammatory pathways

BACKGROUND: Brexanolone has rapid, long-lasting, and remarkable efficacy in the treatment of post-partum depression (PPD). We test the hypothesis that brexanolone inhibits proinflammatory modulators and macrophage activation in PPD patients, which may promote clinical recovery. METHODS: PPD patients...

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Detalles Bibliográficos
Autores principales:	Balan, Irina, Patterson, Riah, Boero, Giorgia, Krohn, Holly, O'Buckley, Todd K., Meltzer-Brody, Samantha, Morrow, A. Leslie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984433/ https://www.ncbi.nlm.nih.gov/pubmed/36801618 http://dx.doi.org/10.1016/j.ebiom.2023.104473

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