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Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma

BACKGROUND: Cavernous angiomas (CAs) affect 0.5% of the population, predisposing to serious neurologic sequelae from brain bleeding. A leaky gut epithelium associated with a permissive gut microbiome, was identified in patients who develop CAs, favoring lipid polysaccharide producing bacterial speci...

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Detalles Bibliográficos
Autores principales: Srinath, Abhinav, Xie, Bingqing, Li, Ying, Sone, Je Yeong, Romanos, Sharbel, Chen, Chang, Sharma, Anukriti, Polster, Sean, Dorrestein, Pieter C., Weldon, Kelly C., DeBiasse, Dorothy, Moore, Thomas, Lightle, Rhonda, Koskimäki, Janne, Zhang, Dongdong, Stadnik, Agnieszka, Piedad, Kristina, Hagan, Matthew, Shkoukani, Abdallah, Carrión-Penagos, Julián, Bi, Dehua, Shen, Le, Shenkar, Robert, Ji, Yuan, Sidebottom, Ashley, Pamer, Eric, Gilbert, Jack A., Kahn, Mark L., D’Souza, Mark, Sulakhe, Dinanath, Awad, Issam A., Girard, Romuald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984539/
https://www.ncbi.nlm.nih.gov/pubmed/36869161
http://dx.doi.org/10.1038/s43856-023-00265-1