MSIMEP: Predicting microsatellite instability from microarray DNA methylation tumor profiles

Deficiency in DNA MMR activity results in tumors with a hypermutator phenotype, termed microsatellite instability (MSI). Beyond its utility in Lynch syndrome screening algorithms, today MSI has gained importance as predictive biomarker for various anti-PD-1 therapies across many different tumor type...

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Detalles Bibliográficos
Autores principales: Santamarina-García, Martín, Brea-Iglesias, Jenifer, Bramsen, Jesper Bertram, Fuentes-Losada, Mar, Caneiro-Gómez, Francisco Javier, Vázquez-Bueno, José Ángel, Lázare-Iglesias, Héctor, Fernández-Díaz, Natalia, Sánchez-Rivadulla, Laura, Betancor, Yoel Z., Ferreiro-Pantín, Miriam, Conesa-Zamora, Pablo, Antúnez-López, José Ramón, Kawazu, Masahito, Esteller, Manel, Andersen, Claus Lindbjerg, Tubio, Jose M.C., López-López, Rafael, Ruiz-Bañobre, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984554/
https://www.ncbi.nlm.nih.gov/pubmed/36879816
http://dx.doi.org/10.1016/j.isci.2023.106127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984554/
https://www.ncbi.nlm.nih.gov/pubmed/36879816
http://dx.doi.org/10.1016/j.isci.2023.106127

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