Cargando…

MSIMEP: Predicting microsatellite instability from microarray DNA methylation tumor profiles

Deficiency in DNA MMR activity results in tumors with a hypermutator phenotype, termed microsatellite instability (MSI). Beyond its utility in Lynch syndrome screening algorithms, today MSI has gained importance as predictive biomarker for various anti-PD-1 therapies across many different tumor type...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santamarina-García, Martín, Brea-Iglesias, Jenifer, Bramsen, Jesper Bertram, Fuentes-Losada, Mar, Caneiro-Gómez, Francisco Javier, Vázquez-Bueno, José Ángel, Lázare-Iglesias, Héctor, Fernández-Díaz, Natalia, Sánchez-Rivadulla, Laura, Betancor, Yoel Z., Ferreiro-Pantín, Miriam, Conesa-Zamora, Pablo, Antúnez-López, José Ramón, Kawazu, Masahito, Esteller, Manel, Andersen, Claus Lindbjerg, Tubio, Jose M.C., López-López, Rafael, Ruiz-Bañobre, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984554/ https://www.ncbi.nlm.nih.gov/pubmed/36879816 http://dx.doi.org/10.1016/j.isci.2023.106127

Ejemplares similares

Clinical, molecular, and immune correlates of the Immunotherapy Response Score in patients with advanced urothelial carcinoma under atezolizumab monotherapy: analysis of the phase II IMvigor210 trial
por: Ferreiro-Pantín, M., et al.
Publicado: (2023)

Clinical significance of baseline Pan-Immune-Inflammation Value and its dynamics in metastatic colorectal cancer patients under first-line chemotherapy
por: Pérez-Martelo, Martín, et al.
Publicado: (2022)

Long-term Response to Nivolumab and Acute Renal Failure in a Patient with Metastatic Papillary Renal Cell Carcinoma and a PD-L1 Tumor Expression Increased with Sunitinib Therapy: A Case Report
por: Ruiz-Bañobre, Juan, et al.
Publicado: (2016)

Ascites-Derived Organoids to Depict Platinum Resistance in Gynaecological Serous Carcinomas
por: Arias-Diaz, Andrea Estrella, et al.
Publicado: (2023)

Differences in expression rather than methylation at placenta-specific imprinted loci is associated with intrauterine growth restriction
por: Monteagudo-Sánchez, Ana, et al.
Publicado: (2019)

3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease
por: Seoane-Viaño, Iria, et al.
Publicado: (2020)

Evaluation of Novel Doxorubicin-Loaded Magnetic Wax Nanocomposite Vehicles as Cancer Combinatorial Therapy Agents
por: Jiménez-López, Julia, et al.
Publicado: (2020)

An analysis of prognostic factors in a cohort of low-grade gliomas and degree of consistency between RTOG and EORTC scores
por: Pérez, Isaura Fernández, et al.
Publicado: (2022)

Somatic mutations in tumor and plasma of locoregional recurrent and/or metastatic head and neck cancer using a next‐generation sequencing panel: A preliminary study
por: Rapado‐González, Óscar, et al.
Publicado: (2022)

Tratamientos farmacológicos de los pacientes con COVID19: interacciones e indicaciones
por: Iglesias, Mercedes, et al.
Publicado: (2020)

The influence of colloidal parameters on the specific power absorption of PAA-coated magnetite nanoparticles
por: Piñeiro-Redondo, Yolanda, et al.
Publicado: (2011)

Comparative analysis of 12 different kits for bisulfite conversion of circulating cell-free DNA
por: Worm Ørntoft, Mai-Britt, et al.
Publicado: (2017)

Aberrant Regulation of Messenger RNA 3′-Untranslated Region in Human Cancer
por: López de Silanes, Isabel, et al.
Publicado: (2007)

Immobilized Gold Nanoparticles Prepared from Gold(III)-Containing Ionic Liquids on Silica: Application to the Sustainable Synthesis of Propargylamines
por: Soengas, Raquel, et al.
Publicado: (2018)

Actigraphy-Based Sleep Parameters in Wheelchair Basketball Athletes: Influence of Training and Competition Load
por: López-Flores, Marcos, et al.
Publicado: (2023)

Percutaneous mitral valve repair in patients developing severe mitral regurgitation early after an acute myocardial infarction: A review
por: Estévez-Loureiro, Rodrigo, et al.
Publicado: (2022)

Securitization, financial stability and effective risk retention. A European analysis
por: Iglesias-Casal, Ana, et al.
Publicado: (2020)

La gestión y relación con los clientes /
por: Robinat Rivadulla, José Ramón
Publicado: (2004)

Microcontroladores Intel MCS-51 : arquitectura y programación
por: Campelo Rivadulla, José Carlos
Publicado: (1998)

Synthesis of P-Stereogenic Benzoazaphosphole 1-Oxides via Alkynylation of P-Stereogenic ortho-Aurated and ortho-Iodo Phosphinic Amides
por: Soengas, Raquel, et al.
Publicado: (2018)

La racionalidad de la guerra : borrador para una crítica de la razón bélica /
por: García Caneiro, José
Publicado: (2000)

Formación humana en primaria /
por: López Iglesias, Yolanda
Publicado: (2002)

Temporary derogation of European environmental legislation for clinical trials of genetically modified organisms (GMOs) for COVID-19
por: Iglesias-Lopez, C.
Publicado: (2020)

Effectiveness of physiotherapy interventions for back care and the prevention of non-specific low back pain in children and adolescents: a systematic review and meta-analysis
por: García-Moreno, José Manuel, et al.
Publicado: (2022)

Impact of the Epigenetically Regulated Hoxa-5 Gene in Neural Differentiation from Human Adipose-Derived Stem Cells
por: Hernández, Rosa, et al.
Publicado: (2021)

Acute Chest Pain and Broad Complex Tachycardia. A Non-typical Case of Pre-excited Atrial Fibrillation
por: Arias, Ramon Suarez, et al.
Publicado: (2011)

Identifying Recurrences Among Non-Metastatic Colorectal Cancer Patients Using National Health Data Registries: Validation and Optimization of a Registry-Based Algorithm in a Modern Danish Cohort
por: Nors, Jesper, et al.
Publicado: (2023)

Actividades preventivas en la mujer. Actualización PAPPS 2022()
por: López García-Franco, Alberto, et al.
Publicado: (2022)

Association between myocardial injury and prognosis of COVID-19 hospitalized patients, with or without heart disease. CARDIOVID registry
por: López-Otero, Diego, et al.
Publicado: (2021)

Asociación entre el daño miocárdico y el pronóstico de pacientes hospitalizados por COVID-19, con y sin cardiopatía. Registro CARDIOVID
por: López-Otero, Diego, et al.
Publicado: (2021)

LC–MS-MS Determination of Cytostatic Drugs on Surfaces and in Urine to Assess Occupational Exposure
por: Lema-Atán, José Ángel, et al.
Publicado: (2022)

Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5
por: Alberdi, Maria, et al.
Publicado: (2017)

Effect of the COVID-19 pandemic on advanced life support units’ prehospital management of the stroke code in four Spanish regions: an observational study
por: Riera-López, Nicolás, et al.
Publicado: (2023)

Longitudinal CTCs gene expression analysis on metastatic castration-resistant prostate cancer patients treated with docetaxel reveals new potential prognosis markers
por: Pereira-Veiga, Thais, et al.
Publicado: (2021)

Atlas de Anatomía Humana.
por: López Antúnez, Luis
Publicado: (1970)

Anatomía funcional del sistema nervioso
por: López Antúnez, Luis
Publicado: (1979)

Atlas de anatomía humana
por: López Antúnez, Luis
Publicado: (1970)

Antibiofilm Efficacy of the Pseudomonas aeruginosa Pbunavirus vB_PaeM-SMS29 Loaded onto Dissolving Polyvinyl Alcohol Microneedles
por: Sillankorva, Sanna, et al.
Publicado: (2022)

Mecp2-Null Mice Provide New Neuronal Targets for Rett Syndrome
por: Urdinguio, Rocio G., et al.
Publicado: (2008)

E-Tongues/Noses Based on Conducting Polymers and Composite Materials: Expanding the Possibilities in Complex Analytical Sensing
por: Sierra-Padilla, Alfonso, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iu0p8rmug0kvpm0n3dgrjb5h3k