Integration of deep learning with Ramachandran plot molecular dynamics simulation for genetic variant classification

Functional classification of genetic variants is a key for their clinical applications in patient care. However, abundant variant data generated by the next-generation DNA sequencing technologies limit the use of experimental methods for their classification. Here, we developed a protein structure a...

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Detalles Bibliográficos
Autores principales: Tam, Benjamin, Qin, Zixin, Zhao, Bojin, Wang, San Ming, Lei, Chon Lok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984559/
https://www.ncbi.nlm.nih.gov/pubmed/36879825
http://dx.doi.org/10.1016/j.isci.2023.106122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984559/
https://www.ncbi.nlm.nih.gov/pubmed/36879825
http://dx.doi.org/10.1016/j.isci.2023.106122

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