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Integration of deep learning with Ramachandran plot molecular dynamics simulation for genetic variant classification
Functional classification of genetic variants is a key for their clinical applications in patient care. However, abundant variant data generated by the next-generation DNA sequencing technologies limit the use of experimental methods for their classification. Here, we developed a protein structure a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984559/ https://www.ncbi.nlm.nih.gov/pubmed/36879825 http://dx.doi.org/10.1016/j.isci.2023.106122 |