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Moesin is an effector of tau-induced actin overstabilization, cell cycle activation, and neurotoxicity in Alzheimer’s disease

In Alzheimer’s disease, neurons acquire phenotypes that are also present in various cancers, including aberrant activation of the cell cycle. Unlike cancer, cell cycle activation in post-mitotic neurons is sufficient to induce cell death. Multiple lines of evidence suggest that abortive cell cycle a...

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Detalles Bibliográficos
Autores principales: Beckmann, Adrian, Ramirez, Paulino, Gamez, Maria, Gonzalez, Elias, De Mange, Jasmine, Bieniek, Kevin F., Ray, William J., Frost, Bess
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984563/
https://www.ncbi.nlm.nih.gov/pubmed/36879821
http://dx.doi.org/10.1016/j.isci.2023.106152