HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8(+)T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a fatal malignant tumor, but effective clinical interventions are limited. PLGA/PEI-mediated DNA vaccine encoding the dual targets of high-mobility group box 1 (HMGB1) or GPC3 was developed for HCC treatment. Compared with PLGA/PEI-GPC3 immunization, PLGA/PEI-HMGB1/...

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Detalles Bibliográficos
Autores principales: Shi, Xiaoqing, Ding, Jiage, Zheng, Yanyan, Wang, Jiawei, Sobhani, Navid, Neeli, Praveen, Wang, Gang, Zheng, Junnian, Chai, Dafei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984564/
https://www.ncbi.nlm.nih.gov/pubmed/36879804
http://dx.doi.org/10.1016/j.isci.2023.106143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984564/
https://www.ncbi.nlm.nih.gov/pubmed/36879804
http://dx.doi.org/10.1016/j.isci.2023.106143

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