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Inhibition of phosphorylated calcium/calmodulin-dependent protein kinase IIα relieves streptozotocin-induced diabetic neuropathic pain through regulation of P2X3 receptor in dorsal root ganglia

Diabetic neuropathic pain (DNP) is frequent among patients with diabetes. We previously showed that P2X3 upregulation in dorsal root ganglia (DRG) plays a role in streptozotocin (STZ)-induced DNP but the underlying mechanism is unclear. Here, a rat model of DNP was established by a single injection...

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Detalles Bibliográficos
Autores principales: He, Xiao-fen, Kang, Yu-rong, Fei, Xue-yu, Chen, Lu-hang, Li, Xiang, Ma, Yi-qi, Hu, Qun-qi, Qu, Si-ying, Wang, Han-zhi, Shao, Xiao-mei, Liu, Bo-yi, Yi-Liang, Du, Jun-Ying, Fang, Jian-qiao, Jiang, Yong-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984656/
https://www.ncbi.nlm.nih.gov/pubmed/34973115
http://dx.doi.org/10.1007/s11302-021-09829-z