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Inhibition of phosphorylated calcium/calmodulin-dependent protein kinase IIα relieves streptozotocin-induced diabetic neuropathic pain through regulation of P2X3 receptor in dorsal root ganglia
Diabetic neuropathic pain (DNP) is frequent among patients with diabetes. We previously showed that P2X3 upregulation in dorsal root ganglia (DRG) plays a role in streptozotocin (STZ)-induced DNP but the underlying mechanism is unclear. Here, a rat model of DNP was established by a single injection...
Autores principales: | He, Xiao-fen, Kang, Yu-rong, Fei, Xue-yu, Chen, Lu-hang, Li, Xiang, Ma, Yi-qi, Hu, Qun-qi, Qu, Si-ying, Wang, Han-zhi, Shao, Xiao-mei, Liu, Bo-yi, Yi-Liang, Du, Jun-Ying, Fang, Jian-qiao, Jiang, Yong-liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984656/ https://www.ncbi.nlm.nih.gov/pubmed/34973115 http://dx.doi.org/10.1007/s11302-021-09829-z |
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