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Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis. Mechanisms and downstream signaling remain incompletely understood. Here, we studied the role of IL‐18 in hepatic stellate cells (HSCs)...

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Detalles Bibliográficos
Autores principales: Knorr, Jana, Kaufmann, Benedikt, Inzaugarat, Maria Eugenia, Holtmann, Theresa Maria, Geisler, Lukas, Hundertmark, Jana, Kohlhepp, Marlene Sophia, Boosheri, Laela M., Chilin‐Fuentes, Daisy R., Birmingham, Amanda, Fisch, Kathleen M., Schilling, Joel D., Loosen, Sven H., Trautwein, Christian, Roderburg, Christoph, Demir, Münevver, Tacke, Frank, Hoffman, Hal M., Feldstein, Ariel E., Wree, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984672/
https://www.ncbi.nlm.nih.gov/pubmed/36059147
http://dx.doi.org/10.1002/hep.32776