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Neuroprotective effect of the calcium channel blocker nilvadipine on retinal ganglion cell death in a mouse ocular hypertension model

We investigated whether nilvadipine has a neuroprotective effect on retinal ganglion cells (RGCs) in a mouse model of ocular hypertension (OH) that expresses cyan fluorescein protein (CFP) in RGCs. OH was induced in the right eyes of Thy1-CFP transgenic mice using a laser. Nilvadipine or vehicle tre...

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Detalles Bibliográficos
Autores principales: Tsuruga, Hidekazu, Murata, Hiroshi, Araie, Makoto, Aihara, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984798/
https://www.ncbi.nlm.nih.gov/pubmed/36879972
http://dx.doi.org/10.1016/j.heliyon.2023.e13812