P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma

MYCN amplification is an independent risk factor for poor prognosis in neuroblastoma (NB), but its protein product cannot be directly targeted because of protein structure. Thus, this study aimed to explore novel ways to indirectly target N-Myc by regulating its post-translational modifications (PTM...

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Detalles Bibliográficos
Autores principales: Cheng, Cheng, He, Tian, Chen, Kai, Cai, Yuanxia, Gu, Yaoyao, Pan, Lijia, Duan, Peiwen, Wu, Yeming, Wu, Zhixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984901/
https://www.ncbi.nlm.nih.gov/pubmed/36708875
http://dx.doi.org/10.1016/j.mcpro.2023.100504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984901/
https://www.ncbi.nlm.nih.gov/pubmed/36708875
http://dx.doi.org/10.1016/j.mcpro.2023.100504

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