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P300 Interacted With N-Myc and Regulated Its Protein Stability via Altering Its Post-Translational Modifications in Neuroblastoma
MYCN amplification is an independent risk factor for poor prognosis in neuroblastoma (NB), but its protein product cannot be directly targeted because of protein structure. Thus, this study aimed to explore novel ways to indirectly target N-Myc by regulating its post-translational modifications (PTM...
Autores principales: | Cheng, Cheng, He, Tian, Chen, Kai, Cai, Yuanxia, Gu, Yaoyao, Pan, Lijia, Duan, Peiwen, Wu, Yeming, Wu, Zhixiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984901/ https://www.ncbi.nlm.nih.gov/pubmed/36708875 http://dx.doi.org/10.1016/j.mcpro.2023.100504 |
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