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The Therapeutic Effect of Tacrolimus in a Mouse Psoriatic Model is Associated with the Induction of Myeloid-derived Suppressor Cells

OBJECTIVES: Topical administration of Tacrolimus (TAC) is efective in the treatment of psoriasis in human patients and in mouse models. Previously, we showed that, though promoting the proliferative expansion of CD4(+)Foxp3(+) regulatory T cells (Tregs), TNFR2 was protective in mouse psoriasis model...

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Detalles Bibliográficos
Autores principales: Chen, Shaokui, Liao, Ping, Xi, Long, Yang, Yang, Wu, Wenzhong, Islam, Md Sahidul, Lin, Zibei, Zheng, Ying, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984933/
https://www.ncbi.nlm.nih.gov/pubmed/36879838
http://dx.doi.org/10.2478/rir-2022-0034