Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expression

Thromboses are major causes of morbidity and mortality in polycythemia vera (PV) and essential thrombocythemia (ET) diseases associated with JAK2(V617F) mutation. However, the molecular mechanism(s) of increased thrombosis in PV and ET remain unknown. Kruppel-like factor 2 (KLF2) is a transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Jihyun, Kim, Soo Jin, Gollamudi, Jahnavi, Thiagarajan, Perumal, Prchal, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984957/
https://www.ncbi.nlm.nih.gov/pubmed/36343116
http://dx.doi.org/10.1182/bloodadvances.2022008052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9984957/
https://www.ncbi.nlm.nih.gov/pubmed/36343116
http://dx.doi.org/10.1182/bloodadvances.2022008052

Ejemplares similares