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A one-step gram-scale protocol for stereoselective domino dimerization to asperazine A analogs
Here, we present an efficient protocol for stereoselective 4N-based domino dimerization in one single step, establishing a 22-membered library of asperazine A analogs. We describe steps for performing a gram-scale 2N-monomer to access the unsymmetrical 4N-dimer. We detail the synthesis of the desire...
Autores principales: | Bai, Leiyang, Fu, Bei, Jiang, Xuefeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985029/ https://www.ncbi.nlm.nih.gov/pubmed/36861828 http://dx.doi.org/10.1016/j.xpro.2023.102114 |
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