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High producer variant of lipoprotein lipase may protect from hepatocellular carcinoma in alcohol-associated cirrhosis

BACKGROUND & AIMS: Progression of alcohol-associated liver disease (ALD) is driven by genetic predisposition. The rs13702 variant in the lipoprotein lipase (LPL) gene is linked to non-alcoholic fatty liver disease. We aimed at clarifying its role in ALD. METHODS: Patients with alcohol-associated...

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Detalles Bibliográficos
Autores principales: Schmalz, Franziska, Fischer, Janett, Innes, Hamish, Buch, Stephan, Möller, Christine, Matz-Soja, Madlen, von Schönfels, Witigo, Krämer, Benjamin, Langhans, Bettina, Klüners, Alexandra, Soyka, Michael, Stickel, Felix, Nattermann, Jacob, Strassburg, Christian P., Berg, Thomas, Lutz, Philipp, Nischalke, Hans Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985032/
https://www.ncbi.nlm.nih.gov/pubmed/36879887
http://dx.doi.org/10.1016/j.jhepr.2023.100684