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High producer variant of lipoprotein lipase may protect from hepatocellular carcinoma in alcohol-associated cirrhosis
BACKGROUND & AIMS: Progression of alcohol-associated liver disease (ALD) is driven by genetic predisposition. The rs13702 variant in the lipoprotein lipase (LPL) gene is linked to non-alcoholic fatty liver disease. We aimed at clarifying its role in ALD. METHODS: Patients with alcohol-associated...
Autores principales: | Schmalz, Franziska, Fischer, Janett, Innes, Hamish, Buch, Stephan, Möller, Christine, Matz-Soja, Madlen, von Schönfels, Witigo, Krämer, Benjamin, Langhans, Bettina, Klüners, Alexandra, Soyka, Michael, Stickel, Felix, Nattermann, Jacob, Strassburg, Christian P., Berg, Thomas, Lutz, Philipp, Nischalke, Hans Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985032/ https://www.ncbi.nlm.nih.gov/pubmed/36879887 http://dx.doi.org/10.1016/j.jhepr.2023.100684 |
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