Histone malonylation is regulated by SIRT5 and KAT2A

The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl donor, a...

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Detalles Bibliográficos
Autores principales: Zhang, Ran, Bons, Joanna, Scheidemantle, Grace, Liu, Xiaojing, Bielska, Olga, Carrico, Chris, Rose, Jacob, Heckenbach, Indra, Scheibye-Knudsen, Morten, Schilling, Birgit, Verdin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
https://www.ncbi.nlm.nih.gov/pubmed/36879797
http://dx.doi.org/10.1016/j.isci.2023.106193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985052/
https://www.ncbi.nlm.nih.gov/pubmed/36879797
http://dx.doi.org/10.1016/j.isci.2023.106193

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