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Histone malonylation is regulated by SIRT5 and KAT2A
The posttranslational modification lysine malonylation is found in many proteins, including histones. However, it remains unclear whether histone malonylation is regulated or functionally relevant. Here, we report that availability of malonyl-co-enzyme A (malonyl-CoA), an endogenous malonyl donor, a...
Autores principales: | Zhang, Ran, Bons, Joanna, Scheidemantle, Grace, Liu, Xiaojing, Bielska, Olga, Carrico, Chris, Rose, Jacob, Heckenbach, Indra, Scheibye-Knudsen, Morten, Schilling, Birgit, Verdin, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985052/ https://www.ncbi.nlm.nih.gov/pubmed/36879797 http://dx.doi.org/10.1016/j.isci.2023.106193 |
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