Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing

BACKGROUND: Immunotherapy has revolutionized cancer treatment, but most patients are refractory to immunotherapy or acquire resistance, with the underlying mechanisms remaining to be explored. METHODS: We characterized the transcriptomes of ~92,000 single cells from 3 pre-treatment and 12 post-treat...

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Detalles Bibliográficos
Autores principales: Hu, Junjie, Zhang, Lele, Xia, Haoran, Yan, Yilv, Zhu, Xinsheng, Sun, Fenghuan, Sun, Liangdong, Li, Shuangyi, Li, Dianke, Wang, Jin, Han, Ya, Zhang, Jing, Bian, Dongliang, Yu, Huansha, Chen, Yan, Fan, Pengyu, Ma, Qiang, Jiang, Gening, Wang, Chenfei, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985263/
https://www.ncbi.nlm.nih.gov/pubmed/36869384
http://dx.doi.org/10.1186/s13073-023-01164-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985263/
https://www.ncbi.nlm.nih.gov/pubmed/36869384
http://dx.doi.org/10.1186/s13073-023-01164-9

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