IL-27 induces autophagy through regulation of the DNMT1/lncRNA MEG3/ERK/p38 axis to reduce pulmonary fibrosis

PURPOSE: Previous studies have shown that interleukin-27 (IL-27) can reduce bleomycin (BLM)-induced pulmonary fibrosis (PF). However, the underlying mechanism by which IL-27 attenuates PF is not fully clear. METHODS: In this research, we used BLM to construct a PF mouse model, and MRC-5 cells stimul...

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Detalles Bibliográficos
Autores principales: Ting, Li, Feng, Yingying, Zhou, Ying, Tong, Zhongkai, Dong, Zhaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985266/
https://www.ncbi.nlm.nih.gov/pubmed/36869378
http://dx.doi.org/10.1186/s12931-023-02373-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985266/
https://www.ncbi.nlm.nih.gov/pubmed/36869378
http://dx.doi.org/10.1186/s12931-023-02373-x

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