Imipenem/cilastatin/relebactam efficacy, safety and probability of target attainment in adults with hospital-acquired or ventilator-associated bacterial pneumonia among patients with baseline renal impairment, normal renal function, and augmented renal clearance

OBJECTIVES: To assess the relationship between renal function and efficacy/safety of imipenem/cilastatin/relebactam for the treatment of hospital-acquired/ventilator-associated pneumonia (HABP/VABP) from RESTORE-IMI 2 and determine the PTA. METHODS: Adults with HABP/VABP were randomized 1:1 to IV im...

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Detalles Bibliográficos
Autores principales: Roberts, Jason A, Nicolau, David P, Martin-Loeches, Ignacio, Deryke, C Andrew, Losada, Maria C, Du, Jiejun, Patel, Munjal, Rizk, Matthew L, Paschke, Amanda, Chen, Luke F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985325/
https://www.ncbi.nlm.nih.gov/pubmed/36880088
http://dx.doi.org/10.1093/jacamr/dlad011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985325/
https://www.ncbi.nlm.nih.gov/pubmed/36880088
http://dx.doi.org/10.1093/jacamr/dlad011

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