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Pioglitazone restores mitochondrial function but does not spare cortical tissue following mild brain contusion

Pioglitazone interacts through the mitochondrial protein mitoNEET to improve brain bioenergetics following traumatic brain injury. To provide broader evidence regarding the therapeutic effects of pioglitazone after traumatic brain injury, the current study is focused on immediate and delayed therapy...

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Detalles Bibliográficos
Autores principales: Hubbard, W Brad, Vekaria, Hemendra J, Kalimon, Olivia J, Spry, Malinda L, Brown, Emily P, Kilbaugh, Todd J, Sullivan, Patrick G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985333/
https://www.ncbi.nlm.nih.gov/pubmed/36879917
http://dx.doi.org/10.1093/braincomms/fcad032