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Protein structure and folding pathway prediction based on remote homologs recognition using PAthreader

Recognition of remote homologous structures is a necessary module in AlphaFold2 and is also essential for the exploration of protein folding pathways. Here, we propose a method, PAthreader, to recognize remote templates and explore folding pathways. Firstly, we design a three-track alignment between...

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Detalles Bibliográficos
Autores principales: Zhao, Kailong, Xia, Yuhao, Zhang, Fujin, Zhou, Xiaogen, Li, Stan Z., Zhang, Guijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985440/
https://www.ncbi.nlm.nih.gov/pubmed/36871126
http://dx.doi.org/10.1038/s42003-023-04605-8