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Molecular-evaluated and explainable drug repurposing for COVID-19 using ensemble knowledge graph embedding

The search for an effective drug is still urgent for COVID-19 as no drug with proven clinical efficacy is available. Finding the new purpose of an approved or investigational drug, known as drug repurposing, has become increasingly popular in recent years. We propose here a new drug repurposing appr...

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Detalles Bibliográficos
Autores principales: Islam, Md Kamrul, Amaya-Ramirez, Diego, Maigret, Bernard, Devignes, Marie-Dominique, Aridhi, Sabeur, Smaïl-Tabbone, Malika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985643/
https://www.ncbi.nlm.nih.gov/pubmed/36871056
http://dx.doi.org/10.1038/s41598-023-30095-z